Ethyl potassium malonate

CAS No. 6148-64-7

Ethyl potassium malonate ( Potassium 3-ethoxy-3-oxopropanoate; Malonic Acid Monoethyl Ester Potassium Salt )

Catalog No. M27553 CAS No. 6148-64-7

Ethyl potassium malonate, a competitive inhibitor of the enzyme succinate dehydrogenase, acts as a precursor to produce (trimethylsilyl)ethyl malonate, which is utilized to prepare beta-ketoesters by acylation and serves as an intermediate for the preparation of ethyl tert-butyl malonate.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Ethyl potassium malonate
  • Note
    Research use only, not for human use.
  • Brief Description
    Ethyl potassium malonate, a competitive inhibitor of the enzyme succinate dehydrogenase, acts as a precursor to produce (trimethylsilyl)ethyl malonate, which is utilized to prepare beta-ketoesters by acylation and serves as an intermediate for the preparation of ethyl tert-butyl malonate.
  • Description
    Ethyl potassium malonate, a competitive inhibitor of the enzyme succinate dehydrogenase, acts as a precursor to produce (trimethylsilyl)ethyl malonate, which is utilized to prepare beta-ketoesters by acylation and serves as an intermediate for the preparation of ethyl tert-butyl malonate.
  • Synonyms
    Potassium 3-ethoxy-3-oxopropanoate; Malonic Acid Monoethyl Ester Potassium Salt
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    mGlu5
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    6148-64-7
  • Formula Weight
    170.2
  • Molecular Formula
    C5H7KO4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    [K+].CCOC(=O)CC([O-])=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Notartomaso S, et al. Expression of the K(+)/Cl(-) cotransporter, KCC2, in cerebellar Purkinje cells is regulated by group-I metabotropic glutamate receptors. Neuropharmacology. 2017 Mar 15;115:51-59.
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